. 2019 Jun 21;55(6):298. doi: 10.3390/medicina55060298

Table 1.

Characteristics of all studies included in the meta-analysis.

First Author	Year	Country	Ethnicity	TB	Source of Control	Genotyping Method	Case/Control	Cases					Controls					HWE (p)
rs3751143 A > C								AA	AC	CC	A	C	AA	AC	CC	A	C
Amiri	2018	Iran	Asian	PTB	PB	PCR-RFLP	100/100	76	21	3	173	27	40	58	2	138	62	<0.001
Ben-Selma	2011	Tunisia	African	PTB	HB	PCR-RFLP	168/150	130	34	4	294	42	104	40	6	248	52	0.395
Ben-Selma	2011	Tunisia	African	EPTB	HB	PCR-RFLP	55/150	19	23	13	61	49	104	40	6	248	52	0.395
Chaudhary	2018	India	Asian	PTB	PB	ARMS-PCR	145/247	63	73	9	199	91	141	95	11	377	117	0.315
Chaudhary	2018	India	Asian	EPTB	PB	ARMS-PCR	100/247	42	42	16	126	74	141	95	11	377	117	0.315
De	2017	India	Asian	PTB	PB	PCR-RFLP	56/60	26	18	12	70	42	36	21	3	93	27	0.978
Fernando	2007	Southeast Asia	Asian	PTB	PB	TaqMan	56/167	34	17	5	85	27	105	55	7	265	69	0.952
Fernando	2007	Southeast Asia	Asian	EPTB	PB	TaqMan	30/167	9	17	4	35	25	105	55	7	265	69	0.952
Fernando	2007	Australia	Caucasian	PTB	PB	TaqMan	49/102	28	21	0	77	21	64	34	4	162	42	0.845
Fernando	2007	Australia	Caucasian	EPTB	PB	TaqMan	50/102	18	28	4	64	36	64	34	4	162	42	0.845
Li	2002	Gambia	African	PTB	HB	PCR-RFLP	325/297	261	58	6	580	70	256	37	4	549	45	0.057
Mokrousov	2008	Russia	Caucasian	PTB	HB	PCR-RFLP	188/126	120	59	9	299	77	96	27	3	219	33	0.511
Nino-Moreno	2007	México	Mixed	PTB	HB	PCR-RFLP	94/110	53	33	8	139	49	70	38	2	178	42	0.215
Ozdemir	2014	Turkey	Asian	PTB	PB	PCR-RFLP	71/160	44	18	9	106	36	76	63	21	215	105	0.176
Ozdemir	2014	Turkey	Asian	EPTB	PB	PCR-RFLP	89/160	47	34	8	128	50	76	63	21	215	105	0.176
Sambasivan	2010	India	Asian	PTB	HB	PCR-RFLP	156/100	89	55	12	233	79	71	21	8	163	37	0.002
Shamsi	2016	Iran	Asian	PTB	HB	PCR-RFLP	100/100	33	66	1	132	68	83	16	1	182	18	0.817
Sharma	2010	India	Asian	PTB	PB	T-ARMS-PCR	181/177	102	75	4	279	83	126	48	3	300	54	0.515
Sharma	2010	India	Asian	EPTB	PB	T-ARMS-PCR	23/177	8	13	2	29	17	126	48	3	300	54	0.515
Singla	2012	India	Asian	PTB	PB	PCR-RFLP	286/392	162	112	12	436	136	258	123	11	639	145	0.420
Singla	2012	India	Asian	EPTB	PB	PCR-RFLP	71/392	45	22	4	112	30	258	123	11	639	145	0.420
Souza de Lima	2016	Brazil	South American	PTB	HB	TaqMan	288/287	170	95	23	435	141	184	89	14	457	117	0.450
Taype	2010	Peru	Caucasian	PTB	HB	PCR-RFLP	498/513	352	130	16	834	162	347	149	17	843	183	0.838
Taype	2010	Peru	Caucasian	EPTB	HB	PCR-RFLP	121/513	82	37	2	201	41	347	149	17	843	183	0.838
Tekin	2010	Turkey	Caucasian	EPTB	HB	PCR-RFLP	74/192	39	28	7	106	42	141	46	5	328	56	0.595
Velayati	2013	Iran	Asian	PTB	HB	PCR- RFLP	79/50	42	35	2	119	39	37	12	1	86	14	0.981
Wu	2015	China	Asian	PTB	PB	PCR-RFLP	103/87	33	49	21	115	91	51	27	9	129	45	0.075
Xiao	2009	China	Asian	PTB	HB	PCR-RFLP	41/384	21	18	2	60	22	221	119	44	561	207	<0.001
Xiao	2009	China	Asian	EPTB	HB	PCR-RFLP	55/384	30	19	6	79	31	221	119	44	561	207	<0.001
Zheng	2017	China	Asian	PTB	PB	TaqMan	1595/1521	972	551	72	2495	695	900	544	77	2344	698	0.655
rs2393799 C > T								CC	CT	TT	C	T	CC	CT	TT	C	T
Amiri	2018	Iran	Asian	PTB	PB	PCR-RFLP	100/100	8	88	4	104	96	4	95	1	103	97	<0.001
Bahari	2013	Iran	Asian	PTB	PB	ARMS-PCR	150/150	71	54	25	196	104	104	40	6	248	52	0.395
Ben-Selma	2011	Tunisia	African	PTB	HB	ARMS-PCR	168/150	16	57	95	89	247	14	51	85	79	221	0.130
Ben-Selma	2011	Tunisia	African	EPTB	HB	ARMS-PCR	55/150	4	15	36	23	87	14	51	85	79	221	0.130
Chaudhary	2018	India	Asian	PTB	PB	ARMS-PCR	145/247	62	67	16	191	99	101	111	35	313	181	0.614
Chaudhary	2018	India	Asian	EPTB	PB	ARMS-PCR	100/247	44	48	8	136	64	101	111	35	313	181	0.614
Li	2002	Gambia	African	PTB	HB	PCR-RFLP	323/347	23	118	182	164	482	44	140	163	228	466	0.111
Mokrousov	2008	Russia	Caucasian	PTB	HB	ARMS	190/127	86	87	17	259	121	65	46	16	176	78	0.093
Nino-Moreno	2007	México	Mixed	PTB	HB	ARMS	92/110	8	32	52	48	136	15	44	51	74	146	0.275
Sambasivan	2010	India	Asian	PTB	HB	PCR-RFLP	156/100	38	88	30	164	148	15	49	36	79	121	0.801
Shamsi	2016	Iran	Asian	PTB	HB	PCR-RFLP	100/100	1	99	0	101	99	6	93	1	105	95	<0.001
Singla	2012	India	Asian	PTB	PB	ARMS	286/392	143	115	28	401	171	231	143	18	605	179	0.485
Singla	2012	India	Asian	EPTB	PB	ARMS	71/392	40	25	6	105	37	231	143	18	605	179	0.485
Songane	2012	Indonesia	Asian	PTB	PB	MassARRAY	842/844	181	413	248	775	909	177	412	255	766	922	<0.001
Velayati	2013	Iran	Asian	PTB	HB	ARMS	79/50	10	67	2	87	71	3	47	0	53	47	<0.001
Wu	2015	China	Asian	PTB	PB	PCR-RFLP	103/87	35	47	21	117	89	9	30	48	48	126	0.202
Xiao	2009	China	Asian	PTB	HB	ARMS	38/384	23	11	4	57	19	208	135	41	551	217	0.009
Xiao	2009	China	Asian	EPTB	HB	ARMS	58/384	40	12	6	92	24	208	135	41	551	217	0.009
Zhou	2018	China	Asain	EPTB	HB	Mass Spectrometry	179/324	81	77	21	239	119	122	143	59	387	261	0.137
rs1718119 G > A								GG	AG	AA	G	A	GG	AG	AA	G	A
Bahari	2013	Iran	Asian	PTB	PB	T-ARMS-PCR	150/150	63	72	15	198	102	66	69	15	201	99	0.622
Zheng	2017	China	Asian	PTB	PB	TaqMan	1568/1454	1090	440	38	2620	516	978	417	59	2373	535	0.087
Zhu	2016	China	Asian	PTB	HB	MassARRAY	467/503	372	91	4	835	99	412	89	2	913	93	0.222
rs208294 G > A								GG	AG	AA	G	A	GG	AG	AA	G	A
Chaudhary	2018	India	Asian	Mixed	PB	PCR-RFLP	245/246	56	147	42	259	231	49	143	54	241	251	0.011
Zheng	2017	China	Asian	PTB	PB	TaqMan	1570/1467	597	732	241	1926	1214	578	679	210	1835	1099	0.642
Zhou	2018	China	Asian	EPTB	HB	Mass Spectrometry	179/324	22	80	77	124	234	70	145	109	285	363	0.099
rs7958311 G > A								GG	AG	AA	G	A	GG	AG	AA	G	A
Zheng	2017	China	Asian	PTB	PB	TaqMan	1533/1503	402	797	334	1601	1465	396	775	332	1567	1439	0.199
Zhu	2016	China	Asian	PTB	HB	MassARRAY	467/503	114	215	138	443	491	137	262	104	536	470	0.300
rs2230911 C > G								CC	CG	GG	C	G	CC	CG	GG	C	G
Souza de Lima	2016	Brazil	South American	PTB	HB	TaqMan	288/288	170	95	23	435	141	193	89	6	475	101	0.245
Zheng	2017	China	Asian	PTB	PB	TaqMan	1565/1509	1029	482	54	2540	590	997	467	45	2461	557	0.274

List of abbreviations: PTB: Pulmonary Tuberculosis; TB: Tuberculosis; EPTB: Extrapulmonary Tuberculosis; PCR-RFLP: PCR-Restriction fragment length polymorphism; ARMS-PCR: Amplification-refractory mutation system-PCR; TaqMan: probes used in quantitative PCR; T-ARMS-PCR: Multiplex Tetra-Primer Amplification Refractory Mutation System-PCR; MassARRAY: Non-fluorescent detection platform utilizing mass spectrometry to accurately measure PCR-derived amplicons.