Table 6.

Results observed for Plackett–Burman Design.

Formulation	Y1 (nm)	Y2	Y3	Y4
PBD1	680	−13	75.36	0.995
PBD2	261	−10	52	0.1815
PBD3	620	−5	58	0.485
PBD4	310	−25.1	53.22	0.32
PBD5	266.9	−18.5	58.21	1.121
PBD6	590	−6	54	0.18
PBD7	380	−26.02	74.42	0.1423
PBD8	383	−22.1	58.93	0.1498
PBD9	490	−6	59	0.1282
PBD10	620	−5.5	76	0.475
PBD11	900	−3.1	71	0.155
PBD12	300	−14	77	1.273

Y₁—average particle size; Y₂—Zeta-potential; Y₃—encapsulation efficiency; Y₄—polydispersity index.