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. 2019 Apr 5;6(2):48. doi: 10.3390/medicines6020048

Figure 1.

Figure 1

In vitro effect of phytochemicals against colorectal cancer by modulation of micro-RNA. Black arrows indicate upregulation while blunted black bars indicate downregulation of selected miRNA by phytochemicals. Overall phytochemical modulation of miRNAs exerts anti-tumorigenic effects either by inhibition of metastasis and invasion, inhibition of cell growth and proliferation, or induction of apoptosis. OncomiRs are shown in red boxes and are downregulated by phytochemicals, while tsmiRs are shown in blue boxes and are upregulated by phytochemicals.