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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Somatic cells reprogramming using Takahashi and Yamanaka’s factors (SOX2, OCT3/4, KLF4, c-MYC) to induced pluripotent stem cells (iPSCs). Induced PSCs can further be used as a novel therapeutic strategy for cell transplantation.