Table 4.
Challenging case broken down by category, comparing myPath and FISH test results with expert histologic evaluation
| Favor malignant | Favor benign | Ambiguous | No. cases | |||
|---|---|---|---|---|---|---|
| Challenging Spitzoid cases | 45 | |||||
| FISH | ||||||
| Positive | 6 | 0 | 6 | Sensitivity | 60% | |
| Negative | 4 | 21 | 6 | Specificity | 100% | |
| No result | 0 | 2 | 0 | Agreement | 87% | |
| MyPath | ||||||
| Malignant | 6 | 1 | 2 | Sensitivity | 67% | |
| Benign | 2 | 20 | 9 | Specificity | 95% | |
| Indeterminate | 1 | 0 | 1 | Agreement | 87% | |
| No result | 1 | 2 | 0 | |||
| Challenging nevoid cases | 17 | |||||
| FISH | ||||||
| Positive | 5 | 0 | 0 | Sensitivity | 63% | |
| Negative | 3 | 4 | 3 | Specificity | 100% | |
| No result | 1 | 1 | 0 | Agreement | 75% | |
| MyPath | ||||||
| Malignant | 4 | 0 | 1 | Sensitivity | 50% | |
| Benign | 1 | 2 | 2 | Specificity | 100% | |
| Indeterminate | 3 | 1 | 0 | Agreement | 54% | |
| No result | 1 | 2 | 0 | |||
| Challenging DPN-like cases | 4 | |||||
| FISH | ||||||
| Positive | 0 | 0 | 1 | |||
| Negative | 0 | 2 | 1 | |||
| MyPath | ||||||
| Malignant | 0 | 0 | 0 | |||
| Benign | 0 | 2 | 2 | |||
| Indeterminate | 0 | 0 | 0 | |||
DPN deep penetrating nevus