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. Author manuscript; available in PMC: 2019 Jul 16.
Published in final edited form as: Acad Emerg Med. 2016 Feb 17;23(3):315–322. doi: 10.1111/acem.12886

Table 3.

Effect sizes for outcome measures associated with PEP before and after 2-hours of treatment in children aged 5 – 17 years with acute asthma exacerbations.

Outcome measure R2 (95% CI) Before treatment a, b P R2 (95% CI) After treatment c, d P
%IOS 1.2 (1.1, 1.4) <0.001 −3.3 (−10.4, 3.7) 0.598
AAIRS 1.7 (1.4, 2.0) <0.001 0.4 (0.1, 0.7) 0.01
%FEV1 −12.1 (−14.9, −9.3) <0.001 −4.2 (−6.3, −2.0) <0.001

Abbreviations: PEP, plethysmograph estimate of pulsus paradoxus; %FEV1, %-predicted forced expiratory volume in 1-second; %IOS, %-predicted airway resistance by impulse oscillometry; AAIRS, acute asthma intensity research score; CI, confidence interval.

a

Effect size for outcome measure across interquartile range of PEP of 34.4% to 48.1%.

b

Multivariable linear regression models adjusted for age, gender, race.

c

Effect size estimates for change of outcome measure after 2-hr of treatment across interquartile range of change of PEP (−10.7% to 1.7%) during this interval.

d

Multivariable linear regression models adjusted for age, gender, race, baseline AAIRS and baseline value of the outcome measure.