Table 1.
Patient characteristics for reports montelukast primary exposures to NPDS for in children aged 5 – 17 years for calendar years 2000 – 2016.
| Patient characteristic | All ingested doses | Ingested doses ≥ 50mg |
|---|---|---|
| Age (median [IQR], years) | 7 [5, 9] | 6 [5, 6] |
| Male gender | 10,907 (64) | 347 (56) |
| Amount ingested | ||
| Median [IQR], mg | 8 [8, 10] | 80 [60, 112] |
| Range, mg | 4 – 445 | 50 – 445 |
| Reason for ingestion | ||
| Unintentional | 16,374 (96) | 481 (78) |
| Intentional | 513 (3) | 130 (21) |
| Management site | ||
| Non-healthcare facility | 16,312 (96) | 390 (63) |
| Patient already en route to healthcare facility | 490 (3) | 175 (28) |
| Referred to a healthcare facility | 138 (1) | 46 (7) |
| Level of care for those referred to healthcare facility | ||
| Treated, evaluated and released | 481 (77) | 170 (77) |
| Admitted to critical care unit | 7 (1) | 4 (2) |
| Admitted to noncritical care unit | 15 (2) | 7 (3) |
| Admitted to psychiatric care unit | 45 (7) | 21 (10) |
| Patient refused referral | 25 (4) | 5 (2) |
| Patient lost to follow up / left AMA | 55 (9) | 14 (6) |
| Treatments applied, | ||
| Cathartic | 5 (0.03) | 2 (0.32) |
| Charcoal, multiple dose | 0 | 0 |
| Charcoal, single dose | 19 (0.11) | 15 (2.4) |
| Cardiopulmonary resuscitation | 0 | 0 |
| Observation only | 17,069 (100) | 618 (100) |
| Medical outcome | ||
| No effect | 16,853 (99) | 283 (46) |
| Minor effect | 52 (0.30) | 42 (7) |
| Moderate effect | 71 (0.42) | 1 (7) |
| Major effect | 38 (0.22) | 0 |
| Death | 0 | 0 |
| Not followed, judged as nontoxic exposure | 6,189 (36) | 73 (12) |
| Not followed, minimal clinical effects possible | 7,610 (45) | 195 (32) |
| Clinical effect judged not due to montelukast | 202 (1) | 9 (1) |
| Clinical effect duration | ||
| Unknown | 16,853 (99) | 575 (93) |
| ≤2 hours | 52 (0.30) | 12 (2) |
| >2 hours to ≤8 hours | 71 (0.42) | 15 (2) |
| >8 hours to ≤24 hours | 38 (0.22) | 10 (2) |
| >24 hours to ≤3 days | 10 (0.06) | 3 (0.5) |
| >3 days to ≤1 week | 2 (0.01) | 3 (0.5) |
Values are n (%) unless otherwise specified.
Percent values may not sum to 100 due to rounding or because they are not mutually exclusive.
Abbreviations: AMA, against medical advice; IQR, interquartile rance; NPDS, National Poison Data System