Table 1.
Results of the review.
| Author (Year) | Features | Field | Statistics | Type |
|---|---|---|---|---|
| Coello-Gomez et al. (2018) [20] | Chlorhexidine gel vs. mouthwash with super-oxidized solution (SOS) | Oral surgery | Not significative | RCT double blinded |
| Sinjari et al. (2018) [21] | Chlorhexidine gel vs. placebo gel for periimplantitis prevention | Implantology; Periodontology | Significative | RCT blinded |
| Rusu et al (2017) [22] | Chlorhexidine-based gingiva-adhering gel containing herbal ingredients vs. 1% chlorhexidine water-soluble gel for periodontitis prevention after scaling | Periodontology | Not significative | RCT blinded |
| Rubio-Palau et al. (2015) [23] | 0.2% Chlorhexidine gel vs. placebo for alveolar osteitis prevention after third molar surgery | Oral surgery | Not Significative | RCT double blind |
| Levin et al. (2015) [24] | Chlorhexidine gel adjunct water jet for periimplantitis prevention | Implantology; periodontology | Not Significative | RCT |
| Jesudasan et al. (2015) [25] | 0.2% Chlorhexidine gel vs. eugenol based paste vs. control for alveolar osteitis prevention after third molar surgery | Oral surgery |
P = 0.002 Eugenol paste has better results |
RCT |
| Haraji et al. (2015) [26] | 0.2% Chlorhexidine after third molar extraction for alveolitis prevention | Oral surgery | Significative, chlorhexidine can reduce pain | RCT split mouth |
| Freudhental et al. (2015) [27] | 0.2% Chlorhexidine vs. placebo for alveolar osteitis prevention | Oral surgery | Not significative | RCT double blinded |
| Diaz-Sanchez et al. [28] | Bioadhesive 0.2% chlorhexidine gel vs. placebo for mucositis radio and chemotherapy induced prevention | Oral surgery; periodontology | Not significative | RCT double blinded |
| Haraji et al. (2014) [29] | 0.2% Chlorhexidine gel vs. control for dry socket (DS) prevention after third molar surgery | Oral surgery |
P = 0.004 Use of chlorhexidine lowered DS |
RCT split mouth |
| Singh et al. (2013) [30] | Calcium hydroxide paste mixed with 2% chlorhexidine gel vs. 2% chlorhexidine gel, vs. calcium hydroxide paste vs. control (no dressing) for intracanal medications | Endodontics | Group I and II P < 0.05 | RCT double blinded |
| Pukallus et al. (2013) [31] | 0.12% Chlorhexidine (CHX) gel vs. 304% fluoride toothpaste to prevent early childhood caries | Prophylaxis | Not significative | RCT |
| Lima et al. (2013) [32] | 1% Chlorhexidine gel vs. calcium hydroxide/camphorated paramonochlorophenol (Callen PMCC) vs. a one-visit endodontic treatment to bacterial proliferation | Endodontics | Chlorhexidine vs. mutans streptococci P = 0.10; PMCC vs. anaerobic bacteria P = 0.002 |
RCT split mouth |
| De Siena et al. (2013) [33] | 1% Chlorhexidine gel vs. 0.2% chlorhexidine for peri-implant mucositis treatment | Implantology; Periodontology | Not significative | Observational study |
| De Lucena et al. (2013) [34] | Calcium hydroxide paste (CH) vs. chlorhexidine gel (CHX-gel) (5.0%) vs. chlorhexidine/gutta-percha points (CHX-GP) vs. octenidine gel (OCT-gel) (5.0%) for dentin E. faecalis contamination preventing | Endodontics; Restorative dentistry | CHX-gel and OCT-gel significative | RCT |
| Almeida et al. (2012) [35] | 5.25% Sodium hypochlorite (NaOCl) or 2% chlorhexidine gel (CHX) for apical periodontitis preventing | Endodontics; Periodontology | Not significative | RCT |
| Heitz-Mayfield et al. (2011) [36] | 0.5% Chlorhexidine gel vs. placebo gel for peri-implant mucositis managing | Implantology; Periodontology | Significative | RCT double blinded |
| Torres-Lagares et al. (2010) [37] | 0.2% Chlorhexidine gel vs. placebo for postextractive alveolitis prevention after third molar extraction on bleeding disorders patients [38,39] | Oral surgery | Significative | RCT double blinded |
| Slot et al. (2010) [40] | 1% Chlorhexidine gel vs. 0.12% chlorhexidine dentifrice-gel vs. control dentifrice vs. 0.2% chlorhexidine mouthwash for plaque formation prevention | Prophylaxis | 1% Chlorhexidine gel and 0.2% chlorhexidine mouthwash were significative | RCT |
| Lopez-Jornet et al. (2010) [41] | Polyvinylpyrrolidone-sodium hyaluronate (Aloclair) gel vs. 0.2% chlorhexidine digluconate gel vs. control for symptom prevention after mucosa biopsy | Oral surgery | Significative | RCT |
| Cabov et al. (2010) [42] | Chlorhexidine gel vs. control to prevent oral mucosa contamination | Oral surgery; Prophylaxis | Significative | RCT double blinded |
| Paolantonio et al. (2009) [43] | Chlorhexidine gel vs. Xantan base chlorhexidine | Oral surgery; prophylaxis | Significative | RCT |
| Malkhassian et al. (2009) [44] | BioPure MTAD vs. 2% Chlorhexidine gel for root canal treatment | Endodontics | Not significative | RCT double blinded |
| Hauser-Gerspach et al. (2009) [45] | Gaseous ozone and chlorhexidine gel for cavities prevention | Prophylaxis | Not significative | RCT |
| Gomes et al. (2009) [46] | 2.5% Sodium hypochlorite (NaOCl) vs. 2% chlorhexidine (CHX) gel on eliminating oral bacteria | Endodontics; Prophylaxis | Not significative | RCT |