Table 7.

Pearson’s linear correlation coefficients between the absolute values of the vIP changes upon SBSs (|ΔvIP|) and the difference in normalized frequency Δν between pathogenic and neutral substitutions

Missense	Synonymous	Intron	UTR
0.68 (<0.05)	0.73 (<0.005)	0.67 (<0.05)	0.49

See legend of Table 3 for further details