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. 2019 Jun 6;11(6):527. doi: 10.3390/v11060527

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Exosomes carrying miRNAs promote NDV spread. (A) NDV titers were detected by plaque assay in DF-1 cells transfected with miRNA mimics and then infected with NDV. (B) The average number of plaques was calculated in DF-1 cells transfected with miRNA mimics and then infected with NDV by the Image-Pro Plus 6.0 software. (C) The mean diameter of plaques in (B) was measured in DF-1 cells transfected with miRNA mimics and then infected with NDV by the Image-Pro Plus 6.0 software. (D) Absorbance was detected by ELISA in DF-1 cells and HeLa cells were transfected with miRNA mimics and then infected with NDV. Error bars are the SEM from three independent experiments. Statistical significance is indicated: ** p < 0.01 and * p < 0.05.