Table 1.
Clinical variables and demographic data from septic patients
| Control (n = 23) | Sepsis (n = 27) | Survival (n = 8) | Non-survival (n = 19) | P valuea S × NS | |
|---|---|---|---|---|---|
| Demographic data | |||||
| Age, mean ± SD, year | 65 ± 14.6 | 62.4 ± 12.8 | 60 ± 15.8 | 63.4 ± 11.6 | 0.5357 |
| Sex (% of male) | 60.9 | 70.4 | 87.5 | 63.2 | 0.3645 |
| Place of acquired infection (%) | |||||
| Prior to ICU | NA | 77.8 | 87.5 | 73.68 | 0.6334 |
| ICU acquired | NA | 22.2 | 12.5 | 26.32 | |
| Severity of disease | |||||
| Septic shock (%) | NA | 77.8 | 87.5 | 73.68 | 0.6334 |
| Severity scores, mean ± SD | |||||
| Apache II | NA | 17.1 ± 6.5 | 15.6 ± 7.6 | 17.7 ± 6 | 0.4483 |
| SOFA | NA | 8.3 ± 2.9 | 8.0 ± 2.9 | 8.4 ± 2.9 | 0.7709 |
| Delta-SOFA (D3-D0) | NA | (−) 0.4 ± 3.1 | (−) 1.9 ± 3.4 | 0.7 ± 2.8 | 0.0666 |
| Organ dysfunction (%) | |||||
| Cardiovascular | NA | 88.9 | 87.5 | 89.5 | 1 |
| Renal | NA | 37 | 37.5 | 36.8 | 1 |
| Respiratory | NA | 85.2 | 75 | 89.5 | 0.5583 |
| Hematological | NA | 11.1 | 0 | 15.8 | 0.5323 |
| Hepatological | NA | 33.3 | 25 | 36.8 | 0.6758 |
| Central nervous system | NA | 44.4 | 50 | 42 | 1 |
| Underlying conditions | |||||
| Chronic comorbidity (%) | |||||
| AIDS | NA | 0 | 0 | 0 | – |
| COPD | NA | 15.4 | 12.5 | 16.7 | 1 |
| Diabetes | NA | 30.8 | 12.5 | 38.9 | 0.3602 |
| Chronic renal disease | NA | 7.7 | 0 | 11.1 | 1 |
| Cardiovascular insufficiency | NA | 11.5 | 0 | 16.7 | 0.5292 |
| Drugs (%) | |||||
| Corticosteroids | NA | 37 | 50 | 31.6 | 0.4147 |
S survivor, NS non-survivor, NA not applicable, SOFA Sequential [Sepsis-related] Organ Failure Assessment, COPD chronic obstructive pulmonary disease
aFisher’s exact test or unpaired t-test were applied to determine the P value when comparing survival and non-survival groups