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. 2019 Jul 15;20:153. doi: 10.1186/s12931-019-1121-z

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — An expanded set of imaging-based metrics including emphysema percentage, tissue fraction at TLC and RV. a Inspirational image-based local structures: θ, Cr, WT*, and D_h*. b Expiration image-based global and lobar function: AirT%. c Inspiration image-based global and lobar function: Emph%. d Global structure:. e Registration-based global and lobar functions:.