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. 2019 Mar 29;12(2):46. doi: 10.3390/ph12020046

Table 2.

Final lipid content (mg/mL) and entrapment efficiency (%EE) of methylene blue-loaded niosomal formulations.

Formulation a Final Lipid Content (mg/mL) %EE
Before Sonication After Sonication
E1
S60: Cho: ELP b
10 22.1 ± 12.7 14.3 ± 1.3
E2
S60: Cho: ELP b
40 32.9 ± 10.1 16.3 ± 3.5
E3
S60: Cho: ELP b
40 40.1 ± 7.9 11.6 ± 4.5
E4
S60: Cho: ELP b
80 27.9 ± 15.8 18.0 ± 14.5
L1
S60: Cho: L90 b
40 10.5 ± 2.4 27.1 ± 1.4

For all experiments, n = 3. a All formulations E1, E2, E3, E4, and L1 were prepared at a molar ratio of 45:45:10. b Span® 60 (S60); cholesterol (Cho); Cremophor® ELP (ELP); Lauroglycol® 90 (L90).