Table 3.

Transgenic zebrafish models for neurodegenerative diseases.

Disease	Gene	Technique	References
Alzheimer’s Disease	appb	Morpholino injection - knockdown	[117]
	psen1	Morpholino injections - knockdown	[121]
	bace2	Zinc-finger nucleases (ZFNs)—knockout	[45]
	psenen	morpholino injection—knockdown	[47]
	apoea	CRISPR-Cas—knockout	[119]
	apoe	morpholino injection (live cell imaging)	[122]
Parkinson’s Disease	djJ-1	morpholino injection—knockdown	[123]
	prkn	gripNAsTM-mediated knockdown	[124]
	pink1	transcription activator-like effector nucleases (TALENs)—knockdown	[125]
	lrrk2	morpholino injection—knockdown	[118]
Amyotrophic Lateral Sclerosis	tardbp (bpt1)	CRISPR-Cas—knockin	[40]
	fus	CRISPR-Cas—knockin	[120]
Huntington’s Disease	htt	morpholino injection—knockdown	[71]