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Recent development of tumor-associated carbohydrate antigen (TACA) vaccines. (a) Multicomponent vaccine containing different TACAs [23,31], (b) entirely carbohydrate-based semi-synthetic vaccine with naturally occurring zwitterionic polysaccharide [34], (c) fully synthetic carbohydrate vaccine containing Pam3CysSerLys4, T-helper epitope, and Tn-MUC1 epitope [7,35].
