SF	Silk Fibroin
SFNs	Silk Fibroin Nanoparticles
PTX	Paclitaxel
SFNs-PTX	Silk Fibroin Nanoparticles loaded with Paclitaxel
rp-UHPLC-MS/MS	reversed phase liquid chromatography coupled to tandem mass spectrometry
LOQ	limit of quantification
LOD	limit of detection
EVs	Extracellular Vesicles
MSC-EVs	Mesenchymal Stem Cell-derived Extracellular Vesicles
API	Active Pharmaceutical Ingredient
PBS	phosphate buffered saline
SEM	Scanning Electron Microscopy
NTA	Nano Tracking Analysis
DLS	Dynamic Light Scattering
PDI	Polydispersity Index
FT-IR	Fourier Transform Infrared
QCs	Quality control samples
HiP	High-Performance Autosampler
SRM	Selected Reaction Monitoring
LLOQ	Lowest Level of Quantification
CV	Coefficient of Variation
RE	Recovery Extraction
EE	Encapsulation (Loading) Efficiency
CFPAC-1	Human pancreatic carcinoma cell line
SD	Standard Deviation
RGD	arginine-glycine-aspartic acid sequence