Table 4.
Detailed description of TCGA tumor datasets having a statistically significant APE1/NPM1 gene expression correlation. Every cohort is represented by its symbol (as shown in Additional file 6: Figure S5), full description, RNA-seq gene expression correlation between APE1 and NPM1 and statistical significance of the data
| Cohort | Description | Corr | P value |
|---|---|---|---|
| PRAD | Prostate adenocarcinoma | 0.644 | 1.58E-59 |
| KICH | Kidney Chromophobe | 0.590 | 1.88E-07 |
| PAAD | Pancreatic adenocarcinoma | 0.517 | 1.41E-13 |
| SARC | Sarcoma | 0.503 | 5.22E-18 |
| GBMLGG | Glioma | 0.501 | 9.73E-44 |
| THYM | Thymoma | 0.462 | 1.07E-07 |
| LUAD | Lung adenocarcinoma | 0.448 | 8.68E-27 |
| THCA | Thyroid carcinoma | 0.445 | 1.00E-25 |
| KIPAN | Pan-kidney cohort (KICH+KIRC+KIRP) | 0.431 | 1.30E-41 |
| KIRP | Kidney renal papillary cell carcinoma | 0.431 | 1.48E-14 |
| STES | Stomach and Esophageal carcinoma | 0.415 | 2.24E-26 |
| STAD | Stomach adenocarcinoma | 0.412 | 1.77E-18 |
| ESCA | Esophageal carcinoma | 0.398 | 2.28E-08 |
| KIRC | Kidney renal clear cell carcinoma | 0.392 | 5.52E-21 |
| CESC | Cervical squamous cell carcinoma and endocervical adenocarcinoma | 0.380 | 7.13E-12 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 0.369 | 4.73E-19 |
| LIHC | Liver hepatocellular carcinoma | 0.348 | 5.09E-12 |
| COAD | Colon adenocarcinoma | 0.344 | 3.87E-14 |
| GBM | Glioblastoma multiforme | 0.306 | 1.17E-04 |
| COADREAD | Colorectal adenocarcinoma | 0.291 | 1.25E-13 |
| BRCA | Breast invasive carcinoma | 0.282 | 1.74E-21 |
| SKCM | Skin Cutaneous Melanoma | 0.270 | 5.76E-03 |
| HNSC | Head and Neck squamous cell carcinoma | 0.264 | 1.04E-09 |
| LUSC | Lung squamous cell carcinoma | 0.246 | 2.31E-08 |
| BLCA | Bladder Urothelial Carcinoma | 0.244 | 6.14E-07 |