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. 2019 Jul 16;17:56. doi: 10.1186/s12915-019-0675-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Silencing of genes functioning in RNA metabolism activates numr-1. a DAVID enrichment analysis of dsRNA clones that increased numr-1p::GFP fluorescence consistently. Complete list of RNAi hits shown in Additional file 8: Table S4. b Representative fluorescence micrographs of worms fed dsRNA targeting RNA metabolism genes that strongly activated the numr-1p::GFP; five worms are shown in each image; scale bar is 100 μm