Table 2.
Patients characteristics, initial management and respiratory impedance by age
| All | < 5 years | ≥5 years | p-value* | |
|---|---|---|---|---|
| n = 12 | n = 6 | n = 6 | ||
| Inborn delivery | 3 (27%) | 3 (42.86%) | 0 (0%) | 0.181 |
| 1-min Apgar score | 6 (4.5–6.5) | 6 (5–7) | 6 (3–6) | 0.309 |
| 5-min Apgar score | 8 (8.0–8.0) | 8 (8.0–8.75) | 7.5 (6.5–8.0) | 0.072 |
| Duration of artificial ventilation, days | 6 (6–13) | 13 (6–15) | 5 (4–7) | 0.104 |
| Total hospitalization length, days | 24 (17.75–35.25) | 24 (17.25–52.50) | 24 (19.25–30.25) | 0.872 |
| Surfactant administration | 3 (30%) | 3 (50%) | 0 (0%) | 0.181 |
| Type of defect sizea | 0.455 | |||
| B | 6 (50%) | 2 (33%) | 4 (66.67%) | |
| C | 5 (41%) | 2 (33%) | 3 (50%) | |
| D | 1 (8%) | 1 (16.67%) | 0 (0%) | |
| Surgical repair | 1.000 | |||
| Primary closure | 9 (75%) | 5 (83.33%) | 4 (66.67%) | |
| Patch reconstruction | 3 (25%) | 1 (16.67%) | 2 (33.33%) | |
| FOT | ||||
| Rrs8 | 9.33 (7.41–12.66) | 12.73 (10.59–14.75) | 7.26 (6.78–8.20) | |
| z-score | 0.25 (−0.03–1.19) | 1.43 (0.48–1.94) | −0.04 (0.12 - -0.31) | 0.015 |
| % predicted | 8.95 (1.90–27.34) | 31.74 (11.08–49.09) | 1.2 (−6.28–8.99) | 0.041 |
| Relative change (% of baseline) | −20.83 (−29.78- -4.46) | −20.83 (−25.70- -16.91) | −14.54 (− 31.31 - -2.9) | 0.930 |
| Z-score change | −0.46 (−2.65–3.74) | −0.46 (− 0.98 - -0.45) | −0.06 (−4.62–13.79) | 0.662 |
| Xrs8 | −4.39 (−5.98- -2.37) | −6.01 (− 6.80- -5.58) | −2.17 (− 2.91- -1.21) | |
| z-score | −1.36 (− 2.87–0.31) | −3 (− 3.85 - -2.61) | 0.33 (− 0.19–0.94) | 0.002 |
| % predicted | 1.35 (− 2.87 - -0.03) | 2.95 (− 3.89- -2.62) | −0.07 (− 0.28–0.83) | 0.002 |
| Relative change (% of baseline) | 31.86 (− 54.25 - -10.62) | 33.59 (− 34.98 - -31.85) | 17.85 (− 65.75- -0.40) | 0.536 |
| Z-score change | − 0.55 (− 0.92–0.16) | − 0.62 (− 0.67 - -0.55) | −0.22 (− 2.19–0.20) | 0.536 |
| AX | 68.04 (32.61–101.37) | 111.49 (82.41–139.61) | 30.46 (12.59–45.77) | |
| z-score | 1.44 (0.32–2.68) | 2.86 (2.03–3.75) | 0.04 (− 1.10–0.63) | 0.002 |
| % predicted | 97.62 (18.0–145.79) | 156.43 (112.58–239.54) | 3.77 (− 53.61–52.06) | 0.004 |
| Relative change (% of baseline) | −32.25 (− 65.8- -10.24) | −32.93 (− 61.74 - -32.25) | − 10.24 (− 72.18–2.42) | 0.428 |
| Z-score change | −0.48 (− 1.15- -0.25) | − 0.48 (− 0.74- -0.37) | −0.41 (− 3.12 - -0.06) | 0.792 |
Data are presented as n (%) or median (25th–75th percentiles). *Fisher information test or Mann-Whitney U test; *one missing value. aCongenital Diaphragmatic Hernia Study Group. Congenital diaphragmatic hernia: defect size correlates with developmental defect. J Pediatr Surg. 2013;48:1177e82. p-values in bold are significant (< 0.05)