Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structure of AAT zoomed in on locations of interest. Presented are some of the missense residues predicted to negatively affect the stability of the folded protein. Several of these missense changes are in the tightly packed core of the protein, such as the P289S variant packed tightly near the M221T variant location
