Table 1.
Control | CCl4 | CCl4/Melatonin | |
---|---|---|---|
ALT, mmoL/(g × L) | 0.45 ± 0.10 | 1.13 ± 0.07 | 0.75 ± 0.04 |
p < 0.01 | p1 < 0.01 | ||
AST, mmoL/(g × L) | 1.70 ± 0.21 | 3.17 ± 0.16 | 2.23 ± 0.60 |
p < 0.01 | p1 < 0.01 | ||
CAT (serum), mcat/L | 14.58 ± 0.40 | 18.93 ± 0.30 | 15.84 ± 0.17 |
p < 0.005 | p1 < 0.001 | ||
CAT (liver), mcat/kg | 4.31 ± 0.11 | 2.71 ± 0.32 | 3.31 ± 0.13 |
p < 0.01 | p1 > 0.05 | ||
SOD, U/g | 4.59 ± 0.10 | 2.95 ± 0.19 | 3.60 ± 0.19 |
p < 0.005 | p1 ≤ 0.05 | ||
LHP, U/g | 1.77 ± 0.14 | 3.05 ± 0.13 | 2.43 ± 0.21 |
p < 0.005 | p1 ≤ 0.05 | ||
TBARS (serum), mmoL/L | 2.18 ± 0.11 | 3.18 ± 0.20 | 2.36 ± 0.05 |
p < 0.01 | p1 < 0.01 | ||
TBARS (liver), mmoL/kg | 3.06 ± 0.10 | 4.40 ± 0.22 | 3.46 ± 0.19 |
p < 0.01 | p1 < 0.05 | ||
CP, mg/L | 230.42 ± 5.35 | 278.54 ± 7.99 | 250.83 ± 12.84 |
p < 0.01 | p1 > 0.05 | ||
GSH (liver), mmoL/kg | 4.20 ± 0.08 | 2.86 ± 0.10 | 3.67 ± 0.14 |
p < 0.005 | p1 < 0.01 | ||
CHO, mmoL/(kg × min) | 8.73 ± 0.28 | 6.65 ± 0.16 | 7.51 ± 0.48 |
p < 0.01 | p1 < 0.01 | ||
SDH, mmoL/(kg × min) | 8.85 ± 0.11 | 6.78 ± 0.11 | 7.51 ± 0.12 |
p < 0.005 | p1 < 0.001 | ||
Urea, mmoL/L | 5.88 ± 0.11 | 3.83 ± 0.23 | 4.39 ± 0.14 |
p < 0.001 | p1 > 0.05 |
Notes: the results are presented as mean ± SD (n = 12); significantly differences: p-versus control, p1-versus CCl4 group. ALT – alanineaminotranferase; AST – aspartateaminotranferase; CAT – catalase; SOD – superoxidedismutase; CP – ceruloplasmine; TBARS – thiobarbaturic acid reactive substances; LHP – lipid hydroperoxides; CHO – cytochromeoxidase; SDH – succinate dehydrogenase; GSH –glutathione.