Figure 2.
Effect of YYB-101 on migration of ovarian cancer cells. (A) A2780/luc (3 × 105) and (B) SKOV3 (1 × 105) cells were seeded in upper chambers. Lower chambers contained 3 μM YYB-101, 80 ng/mL Hepatocyte growth factor (HGF), 80 ng/mL HGF plus 0.3 μM or 3 μM YYB-101, or 80 ng/mL HGF plus 0.1 μM crizotinib. After culture for 48 or 8 h (A2780/luc or SKOV3 cells, respectively), migrated cells were observed using light microscopy. ***p < 0.001 vs. control, one-way ANOVA, followed by Tukey's multiple comparison test.