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Template sequences used in this study and comparison to related literature peptides. (A) Sequences of p53; phage display peptides pDI and pMI; literature stapled peptides SAH-8, M06, and ATSP-7041; and ATSP-7041 variants used as template sequences in this work, MP-292, MP-189, and MP-018. (B) Chemical structure of MP-292, as well as the substructure of the stapling amino acids (R8 and S5) and Aib.
