Figure 3.

RID module bubble removal results at flow rates corresponding to defined WSS in a microfluidic channel. Each data point represents air bubbles successfully removed from a segmented air-liquid flow with bubble volume V_b. The dashed line represents the lower bound of the 95% confidence interval for successful device operation (WSS = 213 dyne cm⁻², Q = 2.6 mL min⁻¹). Air bubbles ranging from 200 nL to 100 μL were successful removed and the maximum air removal rate (dV/dt)_max = 1.5 mL min⁻¹. RID is operational across the physiological WSS range needed for in vitro shear stimulation studies using both human and rodent cells.