Table 1. General Characteristics of the Cohort .
| Variable | All Patients (N = 453) | BMI | ||
|---|---|---|---|---|
| ≤90th Percentile (n = 327) | >90th-97th Percentile (n = 59) | >97th Percentile (n = 67) | ||
| Age at diagnosis, y | ||||
| Mean (SD) | 13.7 (2.7) | 13.6 (2.8) | 13.2 (2.6) | 14.2 (2.0) |
| Median (range) | 14.3 (2.2-17.8) | 14.4 (2.2-17.8) | 13.7 (5.5-16.7) | 14.4 (9.1-17.7) |
| P value | NA | 1 [Reference]a | .27 | .06 |
| Female, No./total No (%) | ||||
| Total cohort | 306/453 (67.5) | 222/327 (67.9) | 38/59 (64.4) | 46/67 (68.7) |
| P value | NA | 1 [Reference] | .65 | >.99 |
| <11 y at MS onset | 33/62 (53.2) | 25/44 (56.8) | 6/12 (50.0) | 2/6 (33.3) |
| P value | NA | 1 [Reference] | .75 | .39 |
| ≥11 y at MS onset | 273/391 (69.8) | 197/283 (69.6) | 32/47 (68.1) | 44/61 (72.1) |
| P value | NA | 1 [Reference] | .86 | .76 |
| Interval first attack to DMT, mo | ||||
| Mean | 11.7 | 11.9 | 11.8 | 10.6 |
| Median | 6.2 | 6.0 | 7.0 | 6.0 |
| No. | 352 | 258 | 40 | 54 |
| P value | NA | 1 [Reference] | .97 | .48 |
| Follow-up duration, mo | ||||
| Mean | 38.4 | 39.1 | 36.8 | 36.4 |
| Median (range) | 31 (1-158) | 31 (1-158) | 31 (1-139) | 30 (2-100) |
| No. | 453 | 327 | 59 | 67 |
| P value | NA | 1 [Reference] | .62 | .39 |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); DMT, disease-modifying therapy; NA, not applicable.
a
1 [Reference], reference group for P value.