Table 3. Adjusted Odds Ratios of Impaired Lung Function and 4-Year Mean Ambient Air Pollutant Concentrations Estimated Using a Spatial Statistical Model Stratified by Breastfed Status.
Pollutant | AOR (95% CI)a,b | P Value for Interaction | |
---|---|---|---|
Not Breastfed (n = 1989) | Breastfed (n = 4751) | ||
FVC <85% of predicted value | |||
PM1 | 2.71 (2.02-3.63) | 1.20 (0.97-1.48) | <.001 |
PM2.5 | 2.27 (1.79-2.88) | 1.26 (1.04-1.51) | <.001 |
PM10 | 1.93 (1.58-2.37) | 1.46 (1.23-1.73) | .02 |
NO2 | 1.87 (1.49-2.36) | 1.69 (1.39-2.04) | .45 |
FEV1 <85% of predicted value | |||
PM1 | 2.81 (2.02-3.90) | 1.46 (1.14-1.87) | .001 |
PM2.5 | 2.64 (2.01-3.47) | 1.55 (1.25-1.92) | .001 |
PM10 | 2.43 (1.93-3.06) | 1.81 (1.49-2.20) | .03 |
NO2 | 2.58 (1.98-3.36) | 2.20 (1.76-2.75) | .31 |
PEF <75% of predicted value | |||
PM1 | 1.74 (1.24-2.45) | 1.27 (0.97-1.66) | .12 |
PM2.5 | 1.56 (1.18-2.08) | 1.21 (0.96-1.52) | .14 |
PM10 | 1.44 (1.12-1.84) | 1.21 (0.98-1.50) | .25 |
NO2 | 1.49 (1.13-1.96) | 1.32 (1.05-1.67) | .47 |
MMEF <75% of predicted value | |||
PM1 | 1.43 (1.06-1.94) | 1.23 (0.98-1.54) | .41 |
PM2.5 | 1.37 (1.06-1.75) | 1.24 (1.02-1.51) | .53 |
PM10 | 1.34 (1.08-1.67) | 1.29 (1.08-1.55) | .78 |
NO2 | 1.37 (1.07-1.75) | 1.40 (1.14-1.72) | .88 |
Abbreviations: AOR, adjusted odds ratio; FEV1, forced expiratory volume in the first second of expiration; FVC, forced vital capacity; MMEF, maximum midexpiratory flow rate; NO2, nitrogen dioxide; PEF, peak expiratory flow rate; PM1, airborne particulate matter with a diameter ≤1 μm; PM2.5, airborne particulate matter with a diameter ≤2.5 μm; PM10, airborne particulate matter with a diameter ≤10 μm.
Adjusted for age, sex, height, birth weight, preterm birth, parental education, annual family income, exercise per week, passive smoke exposure, home coal use, presence of a house pet, home renovation in the past 2 years, area of residence per person, asthma diagnosis, family history of atopy, and short-term air pollution concentrations.
Effect expressed for 1–interquartile range change in ambient concentration for each pollutant (PM1, 13.1 μg/m3; PM2.5, 10.0 μg/m3; PM10, 13.8 μg/m3; and NO2, 7.3 μg/m3).