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. 2019 May 24;2(5):e194186. doi: 10.1001/jamanetworkopen.2019.4186

Table 3. Adjusted Odds Ratios of Impaired Lung Function and 4-Year Mean Ambient Air Pollutant Concentrations Estimated Using a Spatial Statistical Model Stratified by Breastfed Status.

Pollutant AOR (95% CI)a,b P Value for Interaction
Not Breastfed (n = 1989) Breastfed (n = 4751)
FVC <85% of predicted value
PM1 2.71 (2.02-3.63) 1.20 (0.97-1.48) <.001
PM2.5 2.27 (1.79-2.88) 1.26 (1.04-1.51) <.001
PM10 1.93 (1.58-2.37) 1.46 (1.23-1.73) .02
NO2 1.87 (1.49-2.36) 1.69 (1.39-2.04) .45
FEV1 <85% of predicted value
PM1 2.81 (2.02-3.90) 1.46 (1.14-1.87) .001
PM2.5 2.64 (2.01-3.47) 1.55 (1.25-1.92) .001
PM10 2.43 (1.93-3.06) 1.81 (1.49-2.20) .03
NO2 2.58 (1.98-3.36) 2.20 (1.76-2.75) .31
PEF <75% of predicted value
PM1 1.74 (1.24-2.45) 1.27 (0.97-1.66) .12
PM2.5 1.56 (1.18-2.08) 1.21 (0.96-1.52) .14
PM10 1.44 (1.12-1.84) 1.21 (0.98-1.50) .25
NO2 1.49 (1.13-1.96) 1.32 (1.05-1.67) .47
MMEF <75% of predicted value
PM1 1.43 (1.06-1.94) 1.23 (0.98-1.54) .41
PM2.5 1.37 (1.06-1.75) 1.24 (1.02-1.51) .53
PM10 1.34 (1.08-1.67) 1.29 (1.08-1.55) .78
NO2 1.37 (1.07-1.75) 1.40 (1.14-1.72) .88

Abbreviations: AOR, adjusted odds ratio; FEV1, forced expiratory volume in the first second of expiration; FVC, forced vital capacity; MMEF, maximum midexpiratory flow rate; NO2, nitrogen dioxide; PEF, peak expiratory flow rate; PM1, airborne particulate matter with a diameter ≤1 μm; PM2.5, airborne particulate matter with a diameter ≤2.5 μm; PM10, airborne particulate matter with a diameter ≤10 μm.

a

Adjusted for age, sex, height, birth weight, preterm birth, parental education, annual family income, exercise per week, passive smoke exposure, home coal use, presence of a house pet, home renovation in the past 2 years, area of residence per person, asthma diagnosis, family history of atopy, and short-term air pollution concentrations.

b

Effect expressed for 1–interquartile range change in ambient concentration for each pollutant (PM1, 13.1 μg/m3; PM2.5, 10.0 μg/m3; PM10, 13.8 μg/m3; and NO2, 7.3 μg/m3).