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. 2019 May 24;2(5):e194270. doi: 10.1001/jamanetworkopen.2019.4270

Table 3. Sensitivity Analysis for All-Cause Mortality, 2006-2010 Health and Retirement Study.

Life Purpose Score Category Hazard Ratio (95% CI)
First Year Death Exclusion (n = 6985) (723 Events)a Chronic Disease–Free at Baseline (n = 1774) (79 Events)b
Model 3c Model 4d Model 5e Model 6f
1.00-2.99 2.85 (1.85-4.33)g 2.24 (1.44-3.50)g 2.22 (1.10-4.85)g 1.41 (0.59-3.39)
3.00-3.99 1.96 (1.30-2.96)g 1.61 (1.06-2.45)g
4.00-4.99 1.78 (1.20-2.64)g 1.58 (1.06-2.34)g 2.12 (0.94-4.79) 1.76 (0.82-3.77)
5.00-5.99 1.29 (0.85-1.96) 1.24 (0.81-1.90) 1 [Reference] 1 [Reference]
6.00 1 [Reference] 1 [Reference]
P value for trend <.001 .002 .03 .55
a

Sensitivity analysis was conducted by censoring those who died in first year of follow-up (2006). All Cox proportional hazard models were weighted.

b

Sensitivity analysis was conducted by excluding those with chronic disease at baseline. All Cox proportional hazard models were weighted.

c

Cox proportional hazards model analysis after adjusting for age, sex, educational level, race/ethnicity, marital status, smoking status, frequency of physical activity, alcohol consumption, body mass index, functional status, and 1 or more chronic health conditions.

d

Cox proportional hazards model analysis after adjusting for age, sex, educational level, race/ethnicity, marital status, smoking status, frequency of physical activity, alcohol consumption, body mass index, functional status, 1 or more chronic health conditions, depression, anxiety, cynical hostility, and negative affect optimism, positive affect, and social participation.

e

Cox proportional hazards model analysis after adjusting for age, sex, educational level, race/ethnicity, marital status, smoking status, frequency of physical activity, alcohol consumption, body mass index, and functional status.

f

Cox proportional hazards model analysis after adjusting for age, sex, educational level, race/ethnicity, marital status, smoking status, frequency of physical activity, alcohol consumption, body mass index, functional status, depression, anxiety, cynical hostility, negative affect optimism, positive affect, and social participation.

g

P < .05.