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. 2019 May 24;2(5):e194270. doi: 10.1001/jamanetworkopen.2019.4270

Table 4. Data on Cause-Specific Mortality Among 6985 Participants, 2006-2010 Health and Retirement Studya.

Life Purpose Score Category Hazard Ratio (95% CI)
Model 1b Model 2c
Heart, circulatory, and blood conditions
1.00-2.99 2.53 (1.69-3.78)d 2.66 (1.62-4.38)d
3.00-3.99 1.51 (0.92-2.49) 1.56 (0.93-2.62)
4.00-4.99 1.39 (0.87-2.22) 1.40 (0.87-2.27
5.00-6.00 1 [Reference] 1 [Reference]
P value for trend <.001 .02
Cancer and tumors
1.00-2.99 1.49 (0.79-2.80) 1.16 (0.60-2.25)
3.00-3.99 1.11 (0.66-1.86) 0.95 (0.53-1.69)
4.00-4.99 1.16 (0.77-1.74) 1.02 (0.66-1.56)
5.00-6.00 1 [Reference] 1 [Reference]
P value for trend .43 .95
Respiratory tract system conditions
1.00-2.99 3.43 (1.57-7.50)d 1.83 (0.80-4.20)
3.00-3.99 1.68 (0.99-2.86) 1.04 (0.56-1.93)
4.00-4.99 1.62 (1.03-2.54)d 1.24 (0.73-2.11)
5.00-6.00 1 [Reference] 1 [Reference]
P value for trend .02 .40
Digestive tract system conditions
1.00-2.99 2.68 (0.83-9.13) 2.05 (0.52-8.13)
3.00-3.99 5.95 (2.71-13.08)e 4.54 (1.77-11.66)d
4.00-4.99 3.52 (1.57-7.89)d 3.04 (1.34-6.89)d
5.00-6.00 1 [Reference] 1 [Reference]
P value for trend <.001 .01
a

All Cox proportional hazard models were weighted.

b

Cox proportional hazards model analysis after adjusting for age, sex, educational level, race/ethnicity, marital status, smoking status, frequency of physical activity, alcohol consumption, body mass index, functional status, and 1 or more chronic conditions.

c

Cox proportional hazards model analysis after adjusting for age, sex, educational level, race/ethnicity, marital status, functional status, smoking status, frequency of physical activity, alcohol consumption, body mass index, 1 or more chronic health conditions. depression, anxiety, cynical hostility, negative affect, optimism, positive affect, and social participation.

d

P < .05.

e

P < .001.