CPB	Cardiopulmonary bypass
PK	Pharmacokinetics
Vd	Volume of Distribution
SIRS	Systemic Inflammatory Response Syndrome
MODL	Multiple Organ Dysfunction Syndrome
CYP	Cytochrome P450
ECMO	Extracorporeal membrane oxygenation
TNF-α	Tumor necrotic factor-alpha
IL	Interleukin
VV-ECMO	Veno venous extracorporeal membrane oxygenation
VA-ECMO	Veno arterial extracorporeal membrane oxygenation
ICU	Intensive Care Unit
mg	milli grams
mL	milli litre
APACHE	Acute Physiology and Chronic Health Evaluation
SOFA	Sequential Organ Failure Assessment
LC-MS/MS	liquid chromatography tandem mass spectrometry
FDA	Food and Drugs Administration
EMA	European medicines agency
EC	extracorporeal circulations