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AFM characterization of the recombinant human Aβ(M1-42) peptide. The (A) synthetic Aβ(1-42) oligomers and (B) recombinant Aβ(M1-42) oligomers and/or (C) fibrils were prepared from HFIP- treated peptide films in 1× PBS buffer (pH 7.4) and analyzed by atomic force microscopy (AFM). Images (A) and (B) are 2 × 2 μm x–y scale and image (C) is 5 × 5 μm x–y scale. Left. 2-D image. Right. 3-D image.
