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. 2019 Jul 15;19:692. doi: 10.1186/s12885-019-5857-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Overall survival in node-negative cases without chemotherapy. a) Outcome dependent on the tissue level of uPA BH_ST = 0.017. b) Outcome dependent on the tissue level of PAI-1 BH_ST = 0.025. c) Outcome dependent on the occurrence of disseminated cytokeratin positive cells (dCK+). d) Outcome dependent on the occurrence of dCK+ cells and positivity of the proteases uPA and PAI-1 BH_ST = 0.05