Table 1.

Summary of HPCD syntheses in HEBM.

No.	CD	Milling time [h]	B2M ratioa	Productb [g]	DSc	Yieldd [%]
1	β	2	14.6	2.3	4.4	84
2	β	4	14.6	2.3	5.6	78
3	β	3.5	14.6	2.5	5.3	87
4	β-hydrate	3.5	13.0	2.4	3.7	89
5	γ	2	13.2	2.7	5.1	84
6	γ-hydrate	3.5	12.2	2.4	5.5	73

^aBall-to-mass (mass of balls/mass of reagents); ^bisolated, purified; ^ccalculated from the integration of the anomeric-proton and CH₃ signals of ¹H NMR spectra and corrected using the residual solvent content; ^don the base of DS.