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. 2010 Mar 17;30(11):4132–4142. doi: 10.1523/JNEUROSCI.3129-09.2010

Figure 3.

Figure 3.

CaM KD does not alter spontaneous synaptic “mini” release in cultured neurons. A, Representative traces of mEPSCs in control and CaM KD synapses. B, Cumulative probability of the distribution of the mEPSC frequency. The average frequency of mEPSCs in control is 1.34 ± 0.20 Hz (n = 22) and in CaM KD is 1.26 ± 0.21 Hz (n = 28). C, Cumulative probability of the distribution of the mEPSC amplitudes. The average amplitudes of mEPSCs are 10.46 ± 0.49 (n = 22) and 11.22 ± 0.72 (n = 28) in control and CaM KD, respectively. D, Representative traces of mIPSCs in control and CaM KD synapses. E, Cumulative probability of the distribution of the mIPSC frequency. The average frequencies of mEPSCs in control and CaM KD are 2.58 ± 0.32 Hz (n = 24) and 2.26 ± 0.27 Hz (n = 34), respectively. F, Cumulative probability of the distribution of the mIPSC amplitudes. The average amplitudes of mIPSCs are 48.52 ± 2.82 (n = 24) and 44.13 ± 2.63 (n = 34) in control and CaM KD, respectively. Data presented are means ± SEMs; statistical significance was calculated by Student's t test and Kolmogorov–Smirnov test.