Figure 10.

Firing properties of pyramidal cells. A, B, Example of spontaneous discharges in WT (A) and Celsr3|Dlx (B) mice. C–E, Firing rate exhaustion in Celsr3|Dlx mice pyramidal neurons in vivo. C–E, Illustration of this phenomenon in three different Celsr3|Dlx neurons. F, Linear regression analysis of each spike amplitude in function of time for the 21 neurons with firing rate exhaustion. The individual values are illustrated for one of these regression lines. For a convenient illustration, for each neuron, the maximal amplitude calculated by the regression lines has been adjusted at time 0.