Table 3.

Excitability of pyramidal neurons in slices

Parameters	WT (n = 20)	Celsr3 Dlx (n = 19)
Vresting (mV)	−71.2 ± 1.6	−70.3 ± 0.8
Rin (MΩ)	363.4 ± 35.3	399.8 ± 37.1
Cm (pF)	105.5 ± 7.3	100.6 ± 7.3
Threshold current (pA)	90.9 ± 9.1	117.9 ± 10.0*
Threshold voltage (mV)	−40.7 ± 1.6	−32.0 ± 1.4**
Latency of 1st AP (s)	0.08 ± 0.02	0.09 ± 0.02
AHP (mV)	−54.3 ± 1.9	−43.2 ± 1.5**
Half-width (ms)	1.58 ± 0.17	2.47 ± 0.23**
Maximal slope of rise (mV/ms)	261.3 ± 19.8	158.9 ± 11.4**
Maximal slope of fall (mV/ms)	−39.6 ± 3.7	−21.9 ± 2.3**
AP amplitude (mV)	85.9 ± 2.8	68.2 ± 2.2**

AP, Action potential.

*p < 0.05,

**p < 0.01, t test.