Figure 2.
A, B, Immunoprecipitation analysis of the subunit content of α6* (A) and nonα6* (B) nAChR subtypes immunopurified through affinity column from striatal extracts and labeled with 2 nm [3H]Epi. The results are expressed as percentage of total [3H]Epi binding immunoprecipitated by β2 antibody. Each data point is the mean ± SEM of three to five determinations performed in triplicate. Statistical analysis was according to independent-sample Student's t test; **p < 0.01. A, α4: df = 10, t = 3.21, p = 0.009. B, β3: df = 16, t = 4.51, p < 0.001.