Figure 8.
A, B, Effects of intra-VTA perfusion (15 min before nicotine administration) of different concentrations of CntxMII (A) or CntxPIA (B) on habituated locomotion elicited by nicotine (0.4 mg/kg base, i.p.). Mean values are shown. Error bars indicate SEM. Statistical analysis was according to repeated-measures ANOVA. A, *p < 0.05 versus Nic+aCSF. Group size: Saline, five rats; aCSF, six rats; CntxMII (100 nm), five rats; CntxMII (1 μm), five rats; CntxMII (10 μm), six rats. B, *p < 0.05 versus Nic+aCSF. Group size: Saline, five rats; aCSF, seven rats; CntxPIA (1 μm), six rats; CntxPIA (10 μm), four rats.