Table 1.
Composition of nAChR subtypes expressed by DA neurons of dorsal and ventral striatum and ventral midbrain as deduced from immunoprecipitation experiments
nAChR subtype | % of total β2* nAChRs (% of α6* nAChRs) |
||
---|---|---|---|
Dorsal striatum | Ventral striatum | Ventral midbrain | |
α4β2 | 20.5 | 11.3 | 29.8 |
α2α4β2 | 0 | 0 | 8.0 |
α4α5β2 | 39.5 | 53.4 | 32.2 |
α4β2β3 | 6.4 | 1.1 | 8.6 |
α4α6β2β3 | 29.9 (89.0) | 13.7 (40.0) | 21.4 (100.0) |
α6β2β3 | 3.7 (11.0) | 20.5 (60.0) | 0 (0) |
α4* | 96.3 | 79.5 | 100.0 |
α4 (non-α6)* | 66.4 | 65.8 | 78.6 |
α6* | 33.6 | 34.2 | 21.4 |