Figure 1.

The effects of TCF4 rs9960767 genotype on percentage PPI of the acoustic startle response (means and SEM, adjusted for sex and smoking) in 98 British healthy human volunteers (ANCOVA corrected for sex and smoking: ***p < 0.001; A) and in a combined sample of 68 schizophrenia patients and 37 individuals at high risk for schizophrenia from Germany (ANCOVA corrected for sex, smoking, and antipsychotic medication: *p < 0.05; B). SOA30, SOA60, and SOA120, Stimulus onset asynchrony of 30, 60, and 120 ms, respectively, between prepulse and pulse alone.