Figure 8.

No indication of reactive gliosis in Nogo-A^−/− mice. A, B, Representative images of immunostaining with the astrocyte marker GFAP in the dentate gyrus of Nogo-A^+/+ and Nogo-A^−/− mice. C, Quantitative analysis of the GFAP staining. No difference between Nogo-A^−/− and Nogo-A^+/+ mice was detected in the relative optical density of GFAP. All values are mean ± SEM. Scale bar, 200 μm. DG, Dentate gyrus; mPFC, medial prefrontal cortex; CPu, dorsal striatum; NAcC, nucleus accumbens core; NAcS, nucleus accumbens shell; KO, Nogo-A^−/− (n = 4–6); WT, Nogo-A^+/+ (n = 4–6).