Table 2.
Brain glutamate, glutamine, taurine, and GABA levels in Nogo-A−/− and Nogo-A+/+ mice
| GLU | GLN | TAU | GABA | |
|---|---|---|---|---|
| mPFC | ||||
| WT | 108.46 ± 5.28 | 40.73 ± 7.20 | 87.06 ± 3.77 | 15.55 ± 1.03 |
| KO | 101.05 ± 1.62 | 31.86 ± 4.31 | 84.34 ± 4.26 | 14.05 ± 0.36 |
| CPu | ||||
| WT | 84.84 ± 6.24 | 45.76 ± 7.81 | 113.05 ± 6.42 | 15.07 ± 1.23 |
| KO | 76.10 ± 2.58 | 35.53 ± 3.62 | 103.61 ± 5.63 | 13.75 ± 0.50 |
| NAc | ||||
| WT | 74.26 ± 6.06 | 53.11 ± 6.96 | 70.97 ± 6.33 | 54.48 ± 1.89 |
| KO | 65.58 ± 2.14 | 42.74 ± 5.36 | 66.44 ± 3.37 | 45.40 ± 3.64 |
| HPC | ||||
| WT | 87.68 ± 5.22 | 41.58 ± 6.64 | 83.52 ± 4.52 | 23.90 ± 1.37 |
| KO | 81.68 ± 3.32 | 34.13 ± 4.36 | 77.44 ± 4.41 | 21.04 ± 0.98 |
Levels are expressed as mean concentrations in nmol/mg protein. All values are mean ± SEM. GLU, Glutamate; GLN, glutamine; TAU, taurine; mPFC, medial prefrontal cortex; CPu, caudate-putamen; NAc, nucleus accumbens; HPC, hippocampus; KO, Nogo-A−/− (n = 8–10); WT, Nogo-A+/+ (n = 8–10).