Figure 2.

Lyn KO mice have a higher level of extracellular DA in the NAc than WT mice. a, Placement of the recording microelectrode in the core of the NAc of WT (black line) and KO (red lines) mice [diagram adapted from Paxinos and Franklin (2001)]. b, Voltammogram and curve fit representatives of electrically evoked DA changes measured in the core of the NAc slices. c, Stimulation was produced by a double-stimulating electrode system placed 100 μm below the recording electrode. The duration of the stimulation was 0.5 ms, and the amplitude was 0.5 mA. Results are expressed as the mean DA concentration (μm). WT and KO, n = 5, Mann–Whitney test, p < 0.001. d, Results are expressed as the mean of normalized peaks of DA. WT and KO, n = 5. Mann–Whitney test, p < 0.001.