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Effects of mannitol and angiotensin II on mEPSCs in the SON of wild-type and Trpv1−/− mice. Representative examples of the effects of mannitol (A) (60 mm, 372 mOsmol/kg) and angiotensin II (B) (0.1 μm) on mEPSCs in wild-type mice and Trpv1−/− mice (TRPV1KO). All experiments were recorded in the presence of TTX (1 μm). The holding potential was −70 mV. Plots of frequency are single measurements, whereas plots of amplitude are mean ± SEM over 30 s.
