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IFN-α induces prolonged nuclear accumulation of pY-STAT1 and pY-STAT2 in IRF9-deficient MGCs. Immunoblot analysis of nuclear protein lysates from untreated and IFN-α-treated MGCs shows a transient accumulation of pY-STAT1 and pY-STAT2 in WT cells and prolonged accumulation in IRF9-deficient cells.
