Figure 6.

Septate junction proteins are mislocalized in coiled mutants. The figure shows embryonic hindgut from stage 16 wild-type and coiled mutant embryos as indicated. A, In the wild type, NeurexinIV (Nrx IV) is localized to a small stretch of the basolateral membrane. B, In coiled mutant embryos, the NeurexinIV expression domain expands and is found around the entire cell. A similar expansion of the expression domain was observed for Coracle expression (C, D, Cora), Fasciclin III expression (E, F, Fas III), and Discs large expression (G, H, Dlg).