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. 2019 Jul;29(7):1057–1066. doi: 10.1101/gr.243584.118

Figure 2.

Figure 2.

Schematic representation of DNMT3A. The positions of the disease-associated variants included in this study are indicated relative to the protein domain architecture. PWWP, proline-tryptophan-tryptophan-proline domain; ADD, ATRX-Dnmt3-Dnmt3L domain; MTase, Methyltransferase domain; AA, amino acid.