Table 3.
Electrophysiological properties of EGFP-positive WMICs
| Nonadapting with burst (1) | Nonadapting (2) | Adapting with burst (3) | Adapting (4) | Irregular (5) | |
|---|---|---|---|---|---|
| Percentage (%) of all cells (n) | 45 (18) | 17.5 (7) | 12.5 (5) | 10 (4) | 15 (6) |
| Input resistance (MΩ) | 356 ± 220 | 602 ± 257* (vs 3) | 224 ± 26 | 480 ±152 | 616 ± 223* (vs 3) |
| Membrane potential (mV) | 69 ± 9 | 80 ± 8 | 69 ± 5 | 77 ± 12 | 81 ± 7 |
| Threshold potential (mV) | 41 ± 4 | 45 ± 5 | 41 ± 2 | 41 ± 1 | 42 ± 3 |
| Sag (mV) | 2.1 ± 2.2 | 1.5 ± 1 | 3.2 ± 2.2 | 0.7 ± 0.9 | 3 ± 3 |
| Amplitude of 1st AP (mV) | 79 ± 12 | 86 ± 8 | 84 ± 11 | 78 ± 15 | 79 ± 18 |
| Amplitude of 2nd AP (mV) | 77 ± 13 | 81 ± 6 | 80 ± 13 | 76 ± 15 | 76 ± 16 |
| 1st AP half width (ms) | 0.54 ± 0.14 | 0.51 ± 0.09 | 0.5 ± 0.06 | 0.5 ± 0.03 | 0.52 ± 0.11 |
| 2nd AP half width (ms) | 0.6 ± 0.15 | 0.6 ± 0.17 | 0.56 ± 0.07 | 0.51 ± 0.02 | 0.59 ± 0.14 |
| Amplitude of 1st AHP (mV) | 13 ± 6* (vs NAC) | 20 ± 4 | 11 ± 4* (vs 2) | 20 ± 4* (vs 3) | 18 ± 4 |
| Amplitude of 2nd AHP (mV) | 15 ± 4*** (vs 2) | 22 ± 2** (vs 3) | 13 ± 2* (vs 4) | 21 ± 4* (vs 1) | 19 ± 2 |
| Maximal frequency (Hz) | 77.5 ± 35* | 128 ± 51 | 75 ± 34 | 89 ± 20 | 39 ± 20** (vs 2) |
| Early adaptation (%) | 70 ± 11*** (vs 2) | 30 ± 7*** (vs 3) | 77 ± 11*** (vs 4) | 47 ± 5*** (vs 3) | |
| Late adaptation (%) | 6.8 ± 9.5*** (vs 3) | 11 ± 4* (vs 3) | 24 ± 5 | 24 ± 5** (vs 2) |
*p < 0.05, **p < 0.01, ***p < 0.001.