Table 5.
Experimentally observed STN and GPe firing rates and oscillation frequency in monkey models of Parkinson's disease
Number | Experimental measure | Nucleus | Value | n | Source |
---|---|---|---|---|---|
7 | Oscillation minimum firing rate | STN | 0.2 spk/s | 1 | Bergman et al. (1994) |
8 | Mean firing rate | STN | 25.8 ± 14.9 (SD) spk/s | 220 | Bergman et al. (1994) |
9 | Oscillation maximum firing rate | STN | 76.9 spk/s | 1 | Bergman et al. (1994) |
10 | Oscillation minimum firing rate | GPe | 20.7 spk/s | 3 | Raz et al. (2000) |
11 | Mean firing rate | GPe | 44.8 ± 4.6 (SD) spk/s | 445 | Raz et al. (2000) |
12 | Oscillation maximum firing rate | GPe | 117.7 spk/s | 3 | Raz et al. (2000) |
13 | Oscillation frequency | STN & GPe | 15 Hz | 220 | Bergman et al. (1994); Raz et al. (2000) |
The maximum and minimum firing rates of the oscillatory activity for STN and GPe neurons can be extracted from the autocorrelograms used in the cited studies (see supplemental material A, available at www.jneurosci.org). n = number of sample measurements.