Table 2.
Untreated | Drug condition | % decrease | |
---|---|---|---|
Muscimol (0.2–1 μg/μl; n = 10) | |||
BF | −1.111 | −0.134 | 87.9 |
±1 octave | −0.677 | −0.05 | 92.6 |
±2 octave | −0.233 | −0.041 | 82.5 |
Muscimol/SCH50911 (1:1.5; n = 3) | |||
BF | −1.044 | −0.103 | 89.74 |
±1 octave | −0.796 | −0.107 | 86.51 |
±2 octave | −0.621 | −0.079 | 87.24 |
Comparative mean peak amplitudes (millivolts per square millimeters) and relative decrease of the granular sink shown for both pharmacological silencing methods. Note that, although relative decrease is similar in both cases, the amplitudes for nearBF stimulation (±1–2 ocatves) are higher after cortical silencing with muscimol and SCH50911 applied concomitantly.