Figure 7.

Dendritic electrogenesis evoked by long current injection to the distal dendrite and its interaction with somatic action potentials. a, Long (1 s) dendritic current injections near threshold evoking different somatic AP response patterns depending on the distance of dendritic injection site from the soma (electrode placement shown schematically on the left). b, Width of dendritic potentials (DP), including bAPs with dendritic current injection (see Materials and Methods). b–e, Black squares represent the average somatic value. c, Variability of AP firing pattern (coefficient of variation of interspike interval over the entire duration of current injection) due to steady-state current injection as a function of the distance of injection site from the soma. d, Threshold current injection to evoke one or more APs. In some cases, the first AP was initiated at the soma (filled circles) and in other cases at the dendrite (open squares). e, Threshold current required for generating somatic APs with long current injection at the dendrite (D) in proportion to threshold for APs with long current injection at soma (S).